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Antigenic Specificity | GRB10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors (e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isof |
Immunogen | Immunogen: GRB10 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human GRB10, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit GRB10; GRB10; GRB10; GRB-10; Growth factor receptor bound protein 10; GRB 10; GRB10; GRB 10; GRB-10; insulin receptor-binding protein Grb-IR; Grb-IR; Growth factor receptor bound 10] |
Gene, Accession # | [GRB10] |
Catalog # | MBS5312885 |
Price | $345 |
Order / More Info | GRB10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |