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Antigenic Specificity | SORL1 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling |
Immunogen | Immunogen: Purified recombinant fragment of SORL1 (aa2159-2214) expressed in E. Coli. |
Other Names | [SORL1], [SORL1; SORL1; LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32; C11orf32; LDLR relative with 11 ligand-binding repeats; LR11; SorLA] |
Gene, Accession # | [SORL1], Gene ID: 6653, NCBI: NP_003096.1, UniProt: Q92673 |
Catalog # | MBS850606 |
Price | $280 |
Order / More Info | SORL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |