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Antigenic Specificity | PAK7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PAK7 protein. Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human PAK7. |
Other Names | [KIAA1264; p21-activated kinase 7; PAK 7; PAK-5; PAK-7] |
Gene, Accession # | [PAK7], Gene ID: 57144, NCBI: NP_065074.1, UniProt: Q9P286 |
Catalog # | MBS9411310 |
Price | $200, $255 |
Order / More Info | PAK7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |