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Antigenic Specificity | GAPDH |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects the endogenous levels of total GAPDH protein. Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, and ER to Golgi vesicle shuttling. |
Immunogen | Immunogen: A synthetic peptide (conjugated to KLH) corresponding to the C-terminal of human GAPDH. |
Other Names | [GAPDH], [Gapdh; Gapdh; Gapd; Gapd; GAPDH] |
Gene, Accession # | [GAPDH], Gene ID: 24383, NCBI: P04797.3, UniProt: P04797 |
Catalog # | MBS355044 |
Price | $250 |
Order / More Info | GAPDH Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Meyer-Siegler, K., Mauro, D. J., Seal, G., Wurzer, J., deRiel, J. K., Sirover, M. A. A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase. Proc. Nat. Acad. Sci. 88: 8460-8464, 1991. 2. Zheng L, Roeder RG, Luo Y (2003). S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell 114 (2): 255-66. 3. A. Tarze, A. Deniaud, M. Le Bras, E. Maillier, D. Molle, N. Larochette, N. Zamzami, G. Jan, G. Kroemer, and C. Brenner (2007). GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene 26 (18): 2606-2620. |