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Antigenic Specificity | PAP (Prostatic Acid Phophatase), |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.2 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse PAP is a 43,698 dalton protein (381 amino acids; NCBI accession numberAAF23171) associated with prostatic cancer cells, as well as primary afferent sensory neurons involved in the pain pathway. This protein is an enzyme that dephosphorylates adenosine monophosphate (AMP) in the dorsal horn gray matter of the spinal cord, generating free adenosine. Injections of PAP into the dorsal horn of experimental mice has been shown to decrease pain perception by acting in an antinociceptive, antihyperalgesic, and antiallodynic fashion. |
Immunogen | Immunogen: Recombinant mouse PAP protein was expressed using a baculoviral-delivery system. Immunostaining Tissue: Solutions PBS - sodium phosphate-buffered (100 mM; pH 7.2) isotonic (0.9% NaCl, w/v) saline Antibody dilution buffer (PBS with 0.1% non-ionic detergent, such as Triton X-100 or Tween-20). For anti-fading, use Catalog#: MBS555421 or make your won fluorescein anti-fading reagent -- Make up a 2 mg/ml phenylene diamine solution in PBS (phenylene diamine requires extensive vortexing to p |
Other Names | [prostatic acid phosphatase isoform PAP; Prostatic acid phosphatase; prostatic acid phosphatase; acid phosphatase, prostate; 5'-nucleotidase (EC:3.1.3.5); 5'-NT], [ACPP; ACPP; ACP3; 5'-NT; ACP-3; PAP; 5'-NT; TMPase] |
Gene, Accession # | [PAP], Gene ID: 55, NCBI: NP_001090.2 |
Catalog # | MBS555374 |
Price | $430 |
Order / More Info | PAP (Prostatic Acid Phophatase), Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |