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Antigenic Specificity | CD11c Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a genethat encodes for CD11c. This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: E Coli-derived human CD11c recombinant protein (Position: S161-T342). Subcellular Localization: Membrane; Single-pass type I membrane protein. Tissue Specificity: Predominantly expressed in monocytes and granulocytes. |
Other Names | [Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C] |
Gene, Accession # | [CD11c], Gene ID: 3687, NCBI: NP_000878.2, UniProt: P20702 |
Catalog # | MBS1750378 |
Price | $315 |
Order / More Info | CD11c Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |