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Antigenic Specificity | Human VEGFR-2/KDR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
Immunogen | Immunogen: Recombinant human KDR (D1-7). Preparation: Produced from sera of rabbits immunized with highly pure recombinant human soluble extracellular domain of KDR (D1-7) as the immunizing antigen |
Other Names | [human VEGFR-2/KDR; Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR] |
Gene, Accession # | [VEGFR-2/KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS691157 |
Price | $390 |
Order / More Info | Human VEGFR-2/KDR Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Rockl et al., 1998, Exp Cell Res, 241: 161-170]. |