Human DNAM-1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human DNAM-1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human DNAM-1 |
| Clone | [1X20] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Neutr |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DNAX accessory molecule1 (or DNAM1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM1 contains a 236 amino acid (aa) extracellular domain (ECD) with two Ig-like C2 set domains and a 61 aa cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. Within the ECD, human DNAM1 shares 50% and 52% aa sequence identity with mouse and rat DNAM1, respectively. DNAM1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155/PVR and Nectin2/ CD112. Ligation of DNAM1 promotes the activation of NK cells, CD8 + T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelia |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant DNAM-1 extracellular domain. Antigen: Recombinant human DNAM-1 EC domain. |
| Other Names | [CD226; PTA1; DNAM1; DNAM-1; TLiSA1], [CD226; CD226; PTA1; DNAM1; DNAM-1; TLiSA1; DNAM1; DNAM-1] |
| Gene, Accession # | [DNAM-1], Gene ID: 10666, NCBI: NP_006557.2, UniProt: Q15762 |
| Catalog # | MBS690221 |
| Price | $490 |
| Order / More Info | Human DNAM-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies