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Antigenic Specificity | ATMIN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist. The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL |
Immunogen | Immunogen: ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. Buffer: ATMIN Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ATMIN; ASCIZ; ZNF822; KIAA0431; ATM interactor; Zinc finger protein 822; ASCIZ; ATM interactor], [ATMIN; ATMIN; ASCIZ; ZNF822; KIAA0431; ZNF822; ASCIZ] |
Gene, Accession # | [ATMIN], Gene ID: 23300, NCBI: NP_056066, UniProt: O43313 |
Catalog # | MBS153392 |
Price | $375 |
Order / More Info | ATMIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |