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Antigenic Specificity | STING |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STING Antibody detects endogenous levels of STING. Description: Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Acts by recognizing and binding cyclic di-GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced in response to DNA virus in the cytosol: upon binding of c-di-GMP or cGAMP, autoinhibition is alleviated and TMEM173/STING is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression o |
Immunogen | Immunogen: A synthesized peptide derived from human STING. Tissue Specificity: Ubiquitously expressed. Expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophages. |
Other Names | [endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; ERIS; FLJ38577; hMITA; hSTING; Mediator of IRF3 activation; MITA, mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; Stimulator of interferon genes protein; STING; TM173_HUMAN; Tmem173; Transmembrane protein 173] |
Gene, Accession # | [STING], Gene ID: 340061, NCBI: NP_938023.1, UniProt: Q86WV6 |
Catalog # | MBS9611204 |
Price | $225, $280, $340 |
Order / More Info | STING Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |