Edit |   |
Antigenic Specificity | CTNND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catenin delta-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function (1). Catenin delta-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion (2). Catenin delta-1 has both positive and negative effects on cadherin-mediated adhesion (3). Actin dynamics are also regulated by catenin delta-1, which modulates RhoA, Rac, and cdc42 proteins (1). Analogous to beta-catenin, catenin delta-1 translocates to the nucleus |
Immunogen | Immunogen: Recombinant protein of human CTNND1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CAS; CTNND; KIAA0384; P120CAS; P120CTN; p120] |
Gene, Accession # | [CTNND1], Gene ID: 1500, NCBI: NP_001078927.1, UniProt: O60716 |
Catalog # | MBS8503687 |
Price | $310 |
Order / More Info | CTNND1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Reynolds, A.B. and Roczniak-Ferguson, A. (2004) Oncogene 23, 7947-7956. 2. Davis, M. A. et al. (2003) J. Cell Biol. 163, 525-534. 3. Thoreson, M.A. and Reynolds, A.B. (2002) Differentiation 70, 583-589. 4. Anastasiadis, P.Z. and Reynolds, A.B. (2000) J. Cell Sci. 113, 1319-1334. 5. Rush, J. et al. (2005) Nat. Biotechnol. 23, 94-101. |