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Antigenic Specificity | Toll-like receptor 4 (TLR4) (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) α/β and NF-κB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis (7). |
Immunogen | Immunogen: Rabbit polyclonal TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4. |
Other Names | [hToll; CD284 antigen], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | MBS396046 |
Price | $510 |
Order / More Info | Toll-like receptor 4 (TLR4) (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |