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Antigenic Specificity | PSRC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PSRC1 antibody detects endogenous levels of total PSRC1. Description: This gene encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.Function: Required for normal progression through mitosis. Required f |
Immunogen | Immunogen: A synthesized peptide derived from human PSRC1 Subcellular Location: Cytoplasm. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle Pole. Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase. Tissue Specificity: Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus. Not detected in adult skeletal muscle. Predicted Cross Reactivity: |
Other Names | [DDA3; DDA3, mouse, homolog of; Differential display and activated by p53; FP3214; OTTHUMP00000013785; OTTHUMP00000013786; p53-regulated DDA3; Proline/serine-rich coiled-coil 1; Proline/serine-rich coiled-coil protein 1; PSRC1; PSRC1_HUMAN] |
Gene, Accession # | [PSRC1], Gene ID: 84722, NCBI: NP_001005290.1, UniProt: Q6PGN9 |
Catalog # | MBS9608003 |
Price | $240, $280 |
Order / More Info | PSRC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |