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Antigenic Specificity | LAMP-1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Autophagy, the process of bulk degradation of cellular proteins thromugh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome. LAMP-1 shares much homology to LAMP-2 and is thomught to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression. However, the loss of both proteins resulted in embry |
Immunogen | Immunogen: LAMP-1 antibody was raised against a 15 amino acid peptide from near the center of human LAMP-1. Positive Control: Western Blot: EL4 cell lysateImmunofluorescence: Human colon tissue |
Other Names | [LAMP-1; Lysosome associated membrane protein 1], [LAMP1; LAMP1; LAMPA; CD107a; LGP120; LAMP-1; Lysosome-associated membrane protein 1] |
Gene, Accession # | [LAMP-1], Gene ID: 3916, NCBI: NP_005552.3, UniProt: P11279 |
Catalog # | MBS841320 |
Price | $375 |
Order / More Info | LAMP-1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |