Edit |   |
---|---|
Antigenic Specificity | TrkB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Trk (tropomyosin-receptor-kinase) proto-oncogene family of receptor tyrosine kinases contains four members, TrkA, Tr kb, TrkC, and TrkE, which are variably expressed throughout the central and peripheral nervous systems. Tr kb is the high-affinity to the binding brain-derived neurotrophic factor (BDNF) receptor and neurotrophin-4/5 NT-4/5). The binding of BDNF to Tr kb receptor causes many intercellular cascades to be activated such as promoting survival of sensory neurons mainly through Shc site-independent pathways. |
Immunogen | Immunogen: TrkB antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y(p)-F-G) derived from Human TrkB as the immunogen. |
Other Names | [Rabbit TrkB; TrkB; TrkB; Trk B; Phospho Tyr515; Trk-B] |
Gene, Accession # | [TrkB], Gene ID: 4915, NCBI: AAB33109.1 |
Catalog # | MBS5309623 |
Price | $295 |
Order / More Info | TrkB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |