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Antigenic Specificity | EpCAM/CD326/EPG-2/SCLC-CD2 epithelial antigen |
Clone | [GZ-20] |
Host Species | Mouse |
Reactive Species | rat. does not react with human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody GZ-20 is directed against rat EpCAM and recognises an epitope that is distinct from the epitope recognised by the GZ-1 antibody. The GZ-20 antibody does not cross react with human EpCAM. The epithelial cell adhesion molecule (EpCAM), also known as CD326, is a 40 kD glycoprotein that is expressed at the basolateral cell membrane of simple, pseudo-stratified and transitional epithelia of normal adult tissues. EpCAM is reported to function as a homotypic calcium-independent cell adhesion molecule but studies suggest that EpCAM is also involved in cellular processes such as cell signalling, migration, proliferation and differentiation. In humans, EpCAM is overexpressed in a wide range of epithelial carcinomas including lung, colore |
Immunogen | Source Note: GZ-20 is a mouse monoclonal IgG1 antibody derived by fusion of P3-NS1/1-Ag4-1 mouse myeloma cells with splenocytes from a BALB/c mouse immunized with cells derived from the basolateral membrane of rat small intestine. |
Other Names | [epithelial cell adhesion molecule; Epithelial cell adhesion molecule; epithelial cell adhesion molecule; ep-CAM; epithelial glycoprotein 314; tumor-associated calcium signal transducer 1; epithelial cell adhesion molecule; Epithelial glycoprotein 314; EGP314; Protein D5.7A; Tumor-associated calcium signal transducer 1; CD_antigen: CD326], [Epcam; Epcam; Egp314; Tacstd1; Tacstd1; Ep-CAM; EGP314] |
Gene, Accession # | [EpCAM/CD326/EPG-2/SCLC-CD2], Gene ID: 171577, NCBI: NP_612550.1, UniProt: O55159 |
Catalog # | MBS570318 |
Price | $415 |
Order / More Info | EpCAM/CD326/EPG-2/SCLC-CD2 epithelial antigen Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schiechl H, Dohr G.1987. Immunohistochemical studies of the distribution of a basolateral-membrane protein in intestinal epithelial cells (GZ1-Ag) in rats using monoclonal antibodies. Histochemistry. 87:491-8.2. Tarmann T, Dohr G, Schiechl H, Barth S, Hartmann M. 1990. Immunohistochemical detection of an epithelial membrane protein in rat embryos at different stages of development. Acta Anat. 137:141-5. |