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Antigenic Specificity | Mre11 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Mre11 [Murine MAb recognizes Mre11, a 80 kD Mn+2-dependent exonuclease and endonuclease involved in the end-processing of double stranded DNA breaks.]. This antibody recognizes human Mre11, an 80 kD protein that acts as a Mn+2- dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin), and possibly other proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance. |
Immunogen | Antigen: GST fusion protein corresponding to aa 182-582 of Mre11 expressed in E. coli. |
Other Names | [Mre11; Mre11], [Mre11a; Mre11a; Mre11; Mre11] |
Gene, Accession # | Gene ID: 64046, NCBI: NP_071615.1, UniProt: Q9JIM0 |
Catalog # | MBS190331 |
Price | $425 |
Order / More Info | Mre11 Antibody from MYBIOSOURCE INC. |
Product Specific References | Trujillo, KM et al. 1998. J Biol Chem 273: 21447-21450; Carney, JP et al. 1998. Cell 93: 477-486; Moreau, S et al. 1999. Mol Cell Biol 19: 556-566. |