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Antigenic Specificity | NF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NF1 antibody detects endogenous levels of total NF1. Function: Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.Subunit Structure: Interacts with HTR6 (PubMed:23027611).Similarity: Binds phospholipids via its C-terminal CRAL-TRIO domain. Binds primarily glycerophospholipids with monounsaturated C18:1 and/or C16:1 fatty acid moieties and a phosphatidylethanolamine or phosphatidylcholine headgroup. Has lesser affinity for lipids containing phosphatidylserine and phosphatidylinositol. |
Immunogen | Immunogen: A synthesized peptide derived from human NF1 Subcellular Location: Nucleus Tissue Specificity: Detected in brain, peripheral nerve, lung, colon and muscle. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (91%) |
Other Names | [DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS] |
Gene, Accession # | [NF1], Gene ID: 4763, NCBI: NP_000258.1, UniProt: P21359 |
Catalog # | MBS9608998 |
Price | $240, $280 |
Order / More Info | NF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |