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Antigenic Specificity | MAPK6 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle.Structure: In contrast to classical MAPKs, the TXY motif within the activation loop is replaced by the SEG motif, whose phosphorylation activates the MAP kinases.Expression: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 480-530 on human Mitogen-activated protein kinase 6. Conjugation: Unconjugated |
Other Names | [Affinity Purified Mitogen-activated protein kinase 6; ERK3; Extracellular signal regulated kinase p97; Extracellular signal-regulated kinase 3; HsT17250; MAP kinase 6; MAP kinase isoform p97; Mitogen activated protein kinase 6; p97 MAPK; PRKM6; Protein kinase mitogen activated 6] |
Gene, Accession # | [MAPK6], Gene ID: 5597, NCBI: NP_002739.1, UniProt: Q16659 |
Catalog # | MBS5400516 |
Price | $390 |
Order / More Info | MAPK6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |