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Antigenic Specificity | Human PD-L2 |
Clone | [6B7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. Members of the B7 superfamily of counter-receptors were identified by their ability to interact with costimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B71 (CD80), B72 (CD86), B7H1 (PDL1), B7H2 (B7RP1), B7H3, and PDL2 (B7DC). B7 proteins are immunoglobulin (Ig) superfamily members with extracellular IgV-like and IgC-like domains and short cytoplasmic domains. Among the family members, they share from 20-40% amino acid (aa) sequence identity. The cloned human PDL2 cDNA encodes a 273 aa type I membrane precur |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human PD-L2. |
Other Names | [PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2], [PDCD1LG2; PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC] |
Gene, Accession # | [PD-L2], Gene ID: 80380, NCBI: NP_079515.2, UniProt: Q9BQ51 |
Catalog # | MBS690856 |
Price | $490 |
Order / More Info | Human PD-L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |