Edit |   |
Antigenic Specificity | NMDAR2C |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human;Rat. Background: NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations i |
Immunogen | Immunogen: E Coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively. Ig Type: Rabbit IgG |
Other Names | [NMDA 2C; GluN2C; Glutamate [NMDA] receptor subunit epsilon-3; Glutamate Receptor Ionotropic N Methyl D Aspartate 2C; Glutamate receptor ionotropic, NMDA 2C; Glutamate receptor, ionotropic, N methyl D aspartate 2C; Grin2c; N Methly D Aspartate Receptor Channel Subunit Epsilon 3; N Methyl D Aspartate Receptor Subtype 2C; N methyl D aspartate receptor subunit 2C; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NMDE3_HUMAN; NR2C; OTTHUMP00000041930; glutamate receptor, ionotropic, N-methyl D-aspartate 2C], [GRIN2C; GRIN2C; NR2C; GluN2C; NMDAR2C; NMDAR2C; GluN2C; NMDAR2C; NR2C] |
Gene, Accession # | [NMDAR2C], Gene ID: 2905, NCBI: NP_000826.2, UniProt: Q14957 |
Catalog # | MBS178175 |
Price | $280 |
Order / More Info | NMDAR2C Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kalsi G, Whiting P, Bourdelles BL, Callen D, Barnard EA, Gurling H (Apr 1998). Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels. Genomics47 (3): 423-5. doi:10.1006/geno.1997.5132.PMID 9480759. 2. Entrez Gene: GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C. |