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Antigenic Specificity | MRE11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MRE11 Antibody: MRE11 is involved in the repair of DNA double strand breaks as part of a complex that includes the Rad50 and NBS1 protein and is thought to act in the same pathway as the A-T mutated (ATM) protein. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for non-homologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. Mutations in this protein result in a novel ataxia telangiectasia-like disorder ( |
Immunogen | Immunogen: MRE11 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus human MRE11. Buffer: MRE11 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MRE11; ATLD; HNGS1; MRE11; MRE11B; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; MRE11 meiotic recombination 11 homolog A (S. cerevisiae)], [MRE11A; MRE11A; ATLD; HNGS1; MRE11; MRE11B; HNGS1; MRE11; MRE11 homolog 1; MRE11 homolog A] |
Gene, Accession # | [MRE11A], Gene ID: 4361, NCBI: EAW66932, UniProt: P49959 |
Catalog # | MBS150224 |
Price | $375 |
Order / More Info | MRE11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |