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Antigenic Specificity | Human INSULIN-LIKE GROWTH FACTOR I |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml after reconstitution |
Applications | ELISA (EIA), Functional Assays (FN), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human insulin-likegGrowth factor I antibody recognizes human IGF-I (Insulin-like Growth Factor I), a 70 amino acid secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver. IGF-I exhibits both autocrine and paracrine properties and has a widespread effect on cells including those of the bone, cartilage, muscle, nerves, skin, liver and lungs, playing a key role in cell proliferation and growth, inhibition of apoptosis and linked with tumour cell growth. IGF-I signals through binding to the type 1 insulin-like growth factor receptor (IGF-1R) and also to the insulin receptor (IR), resulting in the activation of the AKT signalling pathway. Production of IGF-I is stimulated by growth hormo |
Immunogen | Immunogen: Recombinant human IGF-I Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IGF-I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [insulin-like growth factor I isoform 4 preproprotein; Insulin-like growth factor I; insulin-like growth factor I; IGF-IA; IGF-IB; MGF; insulin-like growth factor IA; insulin-like growth factor IB; mechano growth factor; somatomedin-C; insulin-like growth factor 1 (somatomedin C); Mechano growth factor; MGF; Somatomedin-C], [IGF1; IGF1; IGFI; IGF-I; IGF1A; IBP1; IGF-I; MGF] |
Gene, Accession # | Gene ID: 3479, NCBI: NP_000609.1, UniProt: P05019 |
Catalog # | MBS222757 |
Price | $550 |
Order / More Info | Human INSULIN-LIKE GROWTH FACTOR I Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |