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Antigenic Specificity | EXOSC6 (N-term), 12-38 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6. This gene product constitutes one of the subunits of themultisubunit particle called exosome, which mediates mRNAdegradation. The composition of human exosome is similar to itsyeast counterpart. This protein is homologous to the yeast Mtr3protein. Its exact function is not known, however, it has beenshown using a cell-free RNA decay system that the exosome isrequired for rapid degradation of unstable mRNAs containing AU-richelements (AREs), but not for poly(A) shortening. The exosome doesnot recognize ARE-containing mRNAs on its own, but require |
Immunogen | n/a |
Other Names | [Exosome complex component MTR3; Exosome component 6; mRNA transport regulator 3 homolog; hMtr3; p11; EXOSC6; MTR3] |
Gene, Accession # | [EXOSC6], Gene ID: 118460, NCBI: NP_478126.1, UniProt: Q5RKV6 |
Catalog # | MBS9201834 |
Price | $165, $370 |
Order / More Info | EXOSC6 (N-term), 12-38 Antibody from MYBIOSOURCE INC. |
Product Specific References | Seth, D., et al. J. Hepatol. 48(4):614-627(2008) Lehner, B., et al. Genome Res. 14(7):1315-1323(2004) Raijmakers, R., et al. J. Mol. Biol. 323(4):653-663(2002) van Hoof, A., et al. Curr. Biol. 12 (8), R285-R287 (2002) : Raijmakers, R., et al. J. Mol. Biol. 315(4):809-818(2002) |