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Antigenic Specificity | ABI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participate in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins.ABI1 plays a role in the leukemogenesis by translocating to mlL. |
Immunogen | Immunogen: ABI1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human ABI-1, different from the related rat and Rabbit sequences by one amino acid, as the immunogen |
Other Names | [Affinity Purified Rabbit ABI1; ABI1; ABI1; ABI1; ABI-1; ABI-1; Abi-1; Abelson interactor 1; ABI 1; Abl interactor 1; ABI 1] |
Gene, Accession # | [ABI1], Gene ID: 10006 |
Catalog # | MBS5312523 |
Price | $345 |
Order / More Info | ABI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |