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Antigenic Specificity | VDAC1 |
Clone | [S152B-23] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | ATTO 594 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects a 30 kDa protein. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results) Scientific Background: Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis. |
Immunogen | n/a |
Other Names | [Voltage Dependent Anion Channel 1; Porin; Voltage dependent anion selective channel protein 1; Voltage-dependent anion-selective channel protein 1; hVDAC1; MGC111064; Mitochondrial Porin; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin], [VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1] |
Gene, Accession # | Gene ID: 7416, NCBI: NP_003365.1, UniProt: P21796 |
Catalog # | MBS800925 |
Price | $440 |
Order / More Info | VDAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |