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Antigenic Specificity | PAK6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PAK6 protein. PAK6 encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by PAK6 interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of PAK6 have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PAK6 protein at amino acid sequence of 100-180 |
Other Names | [Rabbit PAK6; Serine/threonine-protein kinase PAK 6; PAK-5; p21-activated kinase 6; PAK-6; PAK6] |
Gene, Accession # | [PAK6], Gene ID: 56924, NCBI: Q9NQU5.1, UniProt: Q9NQU5 |
Catalog # | MBS9710367 |
Price | $130, $220, $325 |
Order / More Info | PAK6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |