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Antigenic Specificity | UNC5C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: UNC5C antibody detects endogenous levels of total UNC5C. Description: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.Subunit Structure: Interacts with the cytoplasmic part of DCC. Interacts (tyrosine phosphorylated form) with PTPN11. Interacts (via extracellular domain) with FLRT3 (via extracellular domain) (By similarity).P |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Membrane. Tissue Specificity: Mainly expressed in brain. Also expressed in kidney. Not expressed in developing or adult lung. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (82%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (91%) |
Other Names | [homolog of C. elegans transmembrane receptor Unc5; Netrin receptor UNC5C; Protein unc 5 homolog C; Protein unc-5 homolog 3; Protein unc-5 homolog C; Unc 5 homolog 3; Unc 5 homolog C; Unc5 (C.elegans homolog) c; Unc5c; UNC5C_HUMAN; UNC5H3] |
Gene, Accession # | [UNC5C], Gene ID: 8633, NCBI: NP_003719.3, UniProt: O95185 |
Catalog # | MBS9603752 |
Price | $240, $280 |
Order / More Info | UNC5C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |