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Antigenic Specificity | Human CD205 |
Clone | [HD30] |
Host Species | Mouse |
Reactive Species | monkey |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD205 antibody, clone HD30 specifically recognizes CD205, otherwise known as DEC205, a type I transmembrane glycoprotein and member of the macrophage mannose receptor family of C-type lectins, predominantly expressed by human dendritic cells. CD205 is a recycled endocytic receptor involved in directing antigen uptake for processing and presentation by MHC class I. CD205 isoforms 2 and 3, generated from the cotranscription of mRNA containing LY75 and CD302 (DCL1), are expressed in malignant Hodgkin's lymphoma cells. |
Immunogen | Immunogen: Purified extracellular domain of human CD205-IgG1 Fc fusion protein. Histology Positive Control Tissue: Human or monkey spleen and lymph node. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse SP2/0-Ag14 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [LY75-CD302 fusion protein isoform 1; Lymphocyte antigen 75; LY75-CD302 fusion protein; DEC-205/DCL-1 fusion; LY75-CD302 readthrough; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD_antigen: CD205], [LY75-CD302; LY75; CD205; CLEC13B; Ly-75] |
Gene, Accession # | [CD205], Gene ID: 100526664, NCBI: NP_001185688.1, UniProt: O60449 |
Catalog # | MBS219678 |
Price | $475 |
Order / More Info | Human CD205 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |