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Antigenic Specificity | WASP / N-WASP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects a 63 kDa* protein corresponding to the molecular mass of WASP on SDS-PAGE immunoblots of Jurkat cell lysate. In rat brain, A431, and SKN-SH cells, this antibody detects a 65 kDa* protein corresponding to the molecular mass of N-WASP. Members of the Wiskott-Aldrich sydrome protein (WASP) family regulate the formation of actin-based cell structures in many cell types. These proteins contain C-terminal actin-binding domains that can stimulate actin polymerization. In addition, these proteins bind the ARP2/3 complex, which can nucleate actin polymerization at sites that lead to branched actin structures. WASP is expressed primarily in hematopoietic cells, while its homolog N-WASP is widely expressed. These proteins have 48 |
Immunogen | Immunogen: A synthetic peptide (coupled to KLH) corresponding to a region near the C-terminus of human WASP. This sequence is highly homologous with a similar region in human N-WASP. |
Other Names | [WASP / N-WASP; Neural Wiskott-Aldrich syndrome protein; WASL], [WASL; WASL; NWASP; N-WASP; MGC48327; DKFZp779G0847] |
Gene, Accession # | Gene ID: 8976, NCBI: NP_003932.3, UniProt: O00401 |
Catalog # | MBS472066 |
Price | $385 |
Order / More Info | WASP / N-WASP Antibody from MYBIOSOURCE INC. |
Product Specific References | • Cory, G.O. et al. (2003) Mol Cell. 11(5):1229-39.• Higgs, H.N. & Pollard, T.D. (2001) Annu Rev Biochem 70:649-676. |