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Antigenic Specificity | ZDHHC7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ZDHHC7 protein. Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.Ota T., Nat. Genet. 36:40-45(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).Sjoeblom T., Science 314:268-274(2006 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human ZDHHC7. |
Other Names | [EC 2.3.1.-; ZDH7; ZDHC7; zinc finger 370; ZNF370] |
Gene, Accession # | [ZDHHC7], Gene ID: 55625, NCBI: NP_001139020.1, UniProt: Q9NXF8 |
Catalog # | MBS9412433 |
Price | $200, $255 |
Order / More Info | ZDHHC7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |