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Antigenic Specificity | Mouse CD11b |
Clone | [mCD11b] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2b |
Format | fluorescein (FITC) conjugate |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of |
Immunogen | Immunogen: Purified mouse LN CD4 T cells. Antibody Properties: Staining and blocking antibody. For staining, use 10 ul/1,000,000 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator. Available Conjugates: This antibody is only available conjugated to FITC. |
Other Names | [CD11b FITC; CD11b FITC, Rat Mouse; Integrin; alpha M; CR3A; MO1A; CD11B; MAC-1; MAC1A; MGC117044; ITGAM TypeRat Mouse; CD11b FITC], [ITGAM; CD11b; CD11B] |
Gene, Accession # | [CD11b], Gene ID: 397459, NCBI: AAB16869.1 |
Catalog # | MBS140037 |
Price | $305, $455 |
Order / More Info | Mouse CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |