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Antigenic Specificity | IGF-IIR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IGF-IIR Polyclonal Antibody detects endogenous levels of IGF-IIR protein. IGF2R encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of |
Immunogen | Immunogen: Synthesized peptide derived from human IGF-IIR around the non-phosphorylation site of S2409 |
Other Names | [Rabbit IGF-IIR; IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor] |
Gene, Accession # | [IGF-IIR], Gene ID: 3482, NCBI: NP_000867.2, UniProt: P11717 |
Catalog # | MBS9705492 |
Price | $130, $220, $325 |
Order / More Info | IGF-IIR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |