FIR Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | FIR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total FIR protein. Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.Nagase T., DNA Res. 5:31-39(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Jandrig B., Oncogene 23:9295-9302(2004). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human FIR. |
| Other Names | [FERM; RhoGEF and pleckstrin domain protein 2; FGD1-related Cdc42-GEF; FIR; FRG] |
| Gene, Accession # | [FIR], Gene ID: 9855, NCBI: NP_001269912.1, UniProt: O94887 |
| Catalog # | MBS9409334 |
| Price | $200, $255 |
| Order / More Info | FIR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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