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Antigenic Specificity | NCOA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Requi |
Immunogen | Immunogen: Recombinant human Nuclear receptor coactivator 1 protein |
Other Names | [Nuclear receptor coactivator 1; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid re; NCOA1; BHLHE74; SRC1] |
Gene, Accession # | [NCOA1], Gene ID: 8648, NCBI: NP_003734.3, UniProt: Q15788 |
Catalog # | MBS7044151 |
Price | $160, $235 |
Order / More Info | NCOA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |