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Antigenic Specificity | PID |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PID antibody is predicted to not cross-react with MTA2. PID Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The transcriptional activity of p53 is modulated by protein stability and acetylation. PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53 |
Immunogen | Immunogen: PID antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PID. Buffer: PID Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PID; PID; MTA1L1; PID; Metastasis-associated protein MTA2; Metastasis-associated 1-like 1; MTA1-L1 protein; metastasis associated 1 family, member 2], [MTA2; MTA2; PID; MTA1L1; MTA1L1; PID; MTA1-L1 protein] |
Gene, Accession # | [MTA2], Gene ID: 9219, NCBI: AAG02241, UniProt: O94776 |
Catalog # | MBS151171 |
Price | $375 |
Order / More Info | PID Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |