CD4 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD4 (cluster of differentiation 4, also known as T-cell antigen T4/LEU3) is a cell surface glycoprotein that is expressed on subsets of thymocytes and mature T lymphocytes, as well as on monocytes and macrophages. CD4 plays an important role in T-helper (Th) cell development and activation.1 Like many cell surface receptors/markers, CD4 is a member of the immunoglobulin superfamily. It has four immunoglobulin domains (D1 to D4) that are exposed on the extracellular surface of the cell. The CD4 antigen is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus.2 HIV-1 uses CD4 to gain entry into host T-cells and achieves this b |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of mouse CD4. |
| Other Names | [CD4], [CD4; CD4; CD4mut; CD4 receptor] |
| Gene, Accession # | [CD4], Gene ID: 920, NCBI: CAA60883.1, UniProt: Q13969 |
| Catalog # | MBS355131 |
| Price | $275 |
| Order / More Info | CD4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Zeitlmann, L., Sirim, P., Kremmer, E., Kolanus, W. Cloning of ACP33 as a novel intracellular ligand of CD4. J. Biol. Chem. 276: 9123-9132, 2001. 2. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, Barclay AN (May 1993). Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains. Science 260 (5110): 979-83. 3. Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA (June 1998). Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393 (6686): 648-59. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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