PKM2 (C-term C474), 460-489 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKM2 (C-term C474), 460-489
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: rabbit)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-489 amino acids from the C-terminal region of human PKM2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Immunogenn/a
Other Names[Pyruvate kinase PKM; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58; PKM; OIP3; PK2; PK3; PKM2]
Gene, Accession #[PKM], Gene ID: 5315, NCBI: NP_001193725.1, UniProt: P14618
Catalog #MBS9211621
Price$165, $370
Order / More InfoPKM2 (C-term C474), 460-489 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLehner, B., et al., Genome Res. 14(7):1315-1323 (2004). Gevaert, K., et al., Nat. Biotechnol. 21(5):566-569 (2003). Valentini, G., et al., J. Biol. Chem. 277(26):23807-23814 (2002). Lowrie, D.J. Jr., et al., J. Struct. Biol. 132(2):83-94 (2000). Williams, J.M., et al., Mol. Microbiol. 27(1):171-186 (1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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