Mouse Shb (C-term), 68-95 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Shb (C-term), 68-95 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse (predicted reactivity: human) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Shb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-95 amino acids from the C-terminal region of mouse Shb. Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells (By similarity). |
| Immunogen | n/a |
| Other Names | [SH2 domain-containing adapter protein B; Shb] |
| Gene, Accession # | [Shb], Gene ID: 230126, NCBI: NP_001028478.1, UniProt: Q6PD21 |
| Catalog # | MBS9203954 |
| Price | $165, $370 |
| Order / More Info | Mouse Shb (C-term), 68-95 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Calounova, G., et al. PLoS ONE 5 (6), E11155 (2010) : Akerblom, B., et al. J. Endocrinol. 203(2):271-279(2009) Mokhtari, D., et al. Biochem. Biophys. Res. Commun. 387(3):553-557(2009) Funa, N.S., et al. Cancer Res. 69(5):2141-2148(2009) Funa, N.S., et al. Differentiation 76(5):443-453(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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