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Antigenic Specificity | Mac-1 (CD11b) (Rat) |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human and mouse Mac-1 (CD11b). The hybridoma was formed by the fusion of mouse myeloma NS1 cells with spleen cells from rats immunized with B10 mouse spleen cells enriched for T-lymphocytes. The antibody is routinely tested by flow cytometry. CD11b is an alpha subunit of Mac-1, also known as CR3. CD11b is the receptor for the C3bi fragment of complement. This receptor is involved in bacterial phagocytosis. A reduction in neutrophil CD11b expression after severe traumatic injury correlates with increased septic complications. CD11b is a component of integrins, important for adhesion of neutrophils to surfaces. Mac-1 exists as a chemoattractant activation-dependent molecule that undergoes a conformational change upon |
Immunogen | Immunogen: B10 mouse spleen cells enriched for T-lymphocytes |
Other Names | [Mac 1] |
Gene, Accession # | [Mac-1] |
Catalog # | MBS4158176 |
Price | $630 |
Order / More Info | Mac-1 (CD11b) (Rat) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |