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Antigenic Specificity | BTBD12 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against BTBD12. It was validated on Western BlotTarget Description: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endon |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD12 |
Other Names | [structure-specific endonuclease subunit SLX4; Structure-specific endonuclease subunit SLX4; structure-specific endonuclease subunit SLX4; SLX4 structure-specific endonuclease subunit; BTB/POZ domain-containing protein 12] |
Gene, Accession # | [SLX4], Gene ID: 84464, NCBI: NP_115820, UniProt: Q8IY92 |
Catalog # | MBS3214540 |
Price | $365 |
Order / More Info | BTBD12 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |