TEAD1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TEAD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TEAD1 antibody detects endogenous levels of total TEAD1. Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%) |
| Other Names | [DTEF 1; NTEF 1; Protein GT-IIC; SV40 transcriptional enhancer factor; TCF 13; TCF13; TEA domain family member 1; TEA domain family member 2; TEA domain family member 3; TEA domain family member 4; TEAD 1; TEAD 2; TEAD 3; TEAD 4; TEAD2; TEAD3; TEAD4; TEAD5; TEF1; TEF4; TEF5; Transcription factor 13; Transcription factor 13 like 1; Transcription factor RTEF 1; Transcriptional enhancer factor TEF 1; Transcriptional enhancer factor TEF 3; Transcriptional enhancer factor TEF 4; Transcriptional enhancer factor TEF 5] |
| Gene, Accession # | [TEAD1], Gene ID: 7003, NCBI: NP_068780.2, UniProt: P28347 |
| Catalog # | MBS9604604 |
| Price | $240, $280 |
| Order / More Info | TEAD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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