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Antigenic Specificity | LCK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. |
Immunogen | Immunogen: LCK antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 394 (N-E-Y(p)-T-A) derived from Human Lck as the immunogen. |
Other Names | [Rabbit LCK; LCK; LCK; Lymphocyte-Specific Protein Tyrosine Kinase; pp58lck; Phospho Tyr394; p56lck; YT16] |
Gene, Accession # | [LCK], Gene ID: 3932, NCBI: AAA59503.1 |
Catalog # | MBS5309543 |
Price | $295 |
Order / More Info | LCK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |