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Antigenic Specificity | HLA-DRB3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding speci |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [HLA-DR3B; MGC117330], [HLA-DRB3; HLA-DRB3; HLA-DR3B] |
Gene, Accession # | [HLA-DRB3], Gene ID: 3125, NCBI: P79483.1, UniProt: P79483 |
Catalog # | MBS126371 |
Price | $200, $275, $430 |
Order / More Info | HLA-DRB3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |