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Antigenic Specificity | PPP1R13L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.1mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73. |
Immunogen | Immunogen: Synthetic peptide of human PPP1R13L Calculated Molecular Weight: 89kDa |
Other Names | [RAI, RAI4, IASPP, NKIP1] |
Gene, Accession # | [PPP1R13L], Gene ID: 10848, NCBI: AAH01475.1 |
Catalog # | MBS2520444 |
Price | $110, $150, $225 |
Order / More Info | PPP1R13L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |