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Antigenic Specificity | Human ADAMTS5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Bat, Gibbon, dog, gorilla, hamster, horse, human, monkey, mouse, rat. predicted reactivity: porcine (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human ADAMTS5. BLAST analysis of the peptide immunogen showed no homology with other human proteins. ADAMTS5, also known as aggrecanase-2, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan. The protein contains a signal sequence, a prodomain with both a potential cysteine switch and a furin cleavage site, a metalloproteinase domain with a conserved zinc-binding motif and a 'met turn,' a disintegrin-like domain, and a spacer region between a thrombospondin type 1 motif and thrombospondin submotif. |
Immunogen | Immunogen Description: Synthetic 18 amino acid peptide from Metalloprotease domain of human ADAMTS5. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse (100%); Pig (94%). |
Other Names | [ADAMTS5 (Metalloprotease Domain) IHC-plus; ADAMTS5; Aggrecanase-2; ADAM-TS 11; ADAM-TS5; ADAMTS-11; ADAMTS11; ADAM-TS 5; ADAMTS-5; ADMP-2; ADMP2; Human ADAMTS5], [ADAMTS5; ADAMTS5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11; ADAMTS11; ADMP2; ADAM-TS 5; ADAM-TS5; ADAMTS-5; ADAM-TS 11; ADAMTS-11] |
Gene, Accession # | [ADAMTS5], Gene ID: 11096, NCBI: NP_008969.2, UniProt: Q9UNA0 |
Catalog # | MBS247770 |
Price | $530 |
Order / More Info | Human ADAMTS5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |