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Antigenic Specificity | MAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAS antibody detects endogenous levels of total MAS. Description: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.Subunit Structure: Interacts with AGTR1. Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA (PubMed:26460884).Similarity: Belongs to the G-protein coupled receptor 1 family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (90%), Sheep (90%), Dog (80%) |
Other Names | [MAS; MAS proto oncogene; Mas-related G protein-coupled receptor A; MAS_HUMAN; Mas1; MAS1 oncogene; MAS1 proto-oncogene, G protein-coupled receptor; MGRA; Proto-oncogene Mas] |
Gene, Accession # | [MAS], Gene ID: 4142, NCBI: NP_002368.1, UniProt: P04201 |
Catalog # | MBS9604332 |
Price | $240, $280 |
Order / More Info | MAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |