MAS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAS
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: MAS antibody detects endogenous levels of total MAS. Description: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.Subunit Structure: Interacts with AGTR1. Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA (PubMed:26460884).Similarity: Belongs to the G-protein coupled receptor 1 family.
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (90%), Sheep (90%), Dog (80%)
Other Names[MAS; MAS proto oncogene; Mas-related G protein-coupled receptor A; MAS_HUMAN; Mas1; MAS1 oncogene; MAS1 proto-oncogene, G protein-coupled receptor; MGRA; Proto-oncogene Mas]
Gene, Accession #[MAS], Gene ID: 4142, NCBI: NP_002368.1, UniProt: P04201
Catalog #MBS9604332
Price$240, $280
Order / More InfoMAS Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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