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Antigenic Specificity | NEFM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NEFM antibody detects endogenous levels of total NEFM. Function: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.Post-translational Modifications: There are a number of repeats of the tripeptide K-S-P, NFM is phosphorylated on a number of the serines in this motif. It is thought that phosphorylation of NFM results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Phosphorylation seems to play a major role in the functioning of the larger neurofilament polypeptides (NF-M and NF-H), the levels of phosphorylation being altered developmentally and coincidentally with a change in the n |
Immunogen | Immunogen: A synthesized peptide derived from human NEFM Subcellular Location: Cytoplasm Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (91%), Xenopus (82%) |
Other Names | [150kDa medium; NEF3; NEFM; Neurofilament 3; NF160; NFM] |
Gene, Accession # | [NEFM], Gene ID: 4741, NCBI: NP_005373.2, UniProt: P07197 |
Catalog # | MBS9608256 |
Price | $240, $280 |
Order / More Info | NEFM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |