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Antigenic Specificity | NGFR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kB and various mitogen-activated protein kinases. Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family. Also known as the low-affinity receptor p75NTR, this receptor is involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. Its ligands include NGF, brain-derived neurotrophic factor (BDNF), NT3, and NT4. NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane doma |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Raised against purified recombinant human NGFR. |
Other Names | [p75NTR, TNFRSF16] |
Gene, Accession # | [NGFR], Gene ID: 4804, NCBI: NP_002498 |
Catalog # | MBS9405408 |
Price | $320 |
Order / More Info | NGFR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |