sh3bp4a (N-term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | sh3bp4a (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | zebrafish |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DANRE sh3bp4a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 132-165 amino acids from the N-terminal region of DANRE sh3bp4a. Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity). |
| Immunogen | n/a |
| Other Names | [SH3 domain-binding protein 4-A; sh3bp4a; sh3bp4] |
| Gene, Accession # | [sh3bp4a], Gene ID: 403082, NCBI: XP_005161754.1, UniProt: Q1LVQ2 |
| Catalog # | MBS9207616 |
| Price | $165, $370 |
| Order / More Info | sh3bp4a (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Howe K.,et al.Nature 496:498-503(2013). Abe S.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. |
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MYBIOSOURCE INC.
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